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We thank C. Richardson and all members of our laboratory for discussions. We also thank B. Seed for discussion and providing the systems to generate recombinant Spike proteins. We thank Q. Zhu, L. Ruan and L. Zhang for sharing unpublished data of SARS coronavirus infection on mice and protocols of virus infections. This work is supported by the Institute for Molecular Biotechnology of the Austrian Academy of Sciences and the Jubilaeumsfonds of the Austrian National Bank. K.K. is supported by a Marie Curie Fellowship from the EU. C.J. is supported by Beijing Committee of Science and Technology grant H030230010930, National Natural Science Foundation of China innovation group grant 30421003 and SARS donation from Joincare Corporation. A.S. is supported in part by the Canadian Institutes of Health Research and the Canada Foundation for Innovation.
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